ADHD Medication During Pregnancy and Breastfeeding
Women with ADHD must make a difficult decision on whether to keep or stop taking
adhd medications for adults medication during pregnancy and breast-feeding. There isn't much information on how long-term exposure to these drugs can affect the foetus.
A recent study published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological problems such as hearing loss or vision, febrile seizures, or IQ impairment. The authors acknowledge that more high quality research is needed.
Risk/Benefit Analysis
Pregnant women who take ADHD medications need to balance the advantages of taking them against the potential risks to the fetus. Physicians don't have the data needed to provide clear recommendations however they can provide information on benefits and risks that can aid pregnant women in making informed choices.
A study published in Molecular Psychiatry concluded that women who took ADHD medication during early pregnancy were not at greater risk of fetal malformations or structural birth defects. Researchers used a vast, population-based case-control study to evaluate the incidence of major structural birth defects in infants born to mothers who had taken stimulants in early pregnancy, as well as those who had not. Pediatric cardiologists, clinical geneticists and other experts examined the cases to confirm that the classification was accurate and to minimize any bias.
However, the study had its limitations. Most important, they were unable to separate the effects of the medication from the effects of the underlying disorder. This makes it difficult for researchers to determine whether the small differences observed between the groups exposed were due to medication use or confounded by the presence of comorbidities. Additionally, the researchers did not look at the long-term effects of offspring on their parents.
The study did show that infants whose mothers took
common adhd medications medications during pregnancy were at slightly more risk of being admitted to the neonatal intensive care unit (NICU) than infants whose mothers had not taken any medication or had taken off their medication prior to or during pregnancy. This was due to central nervous system-related disorders, and the higher risk of admission did not appear to be influenced by which stimulant medication was used during pregnancy.
Women who were taking stimulant ADHD medications during pregnancy also had a higher chance of having an emergency caesarean section or having one whose baby scored low on the Apgar scale (less than 7). These increases did appear to be independent of the type of medication taken during pregnancy.
The researchers suggest that the low risk associated with the use of ADHD medications during the early stages of pregnancy could be offset by the higher benefit for both mother and child from continued treatment for the woman's condition. Physicians should discuss the issue with their patients and, when possible, assist them in developing strategies for improving their coping skills that can lessen the effects of her disorder on her daily life and relationships.
Medication Interactions
As more women than ever are diagnosed with ADHD and treated with medication, the dilemma of whether to continue or end treatment during pregnancy is a question that more and more doctors face. These decisions are usually made without clear and reliable evidence. Instead, physicians must take into account their own experience, the experience of other physicians and the research on the subject.
The issue of risk to the infant can be difficult to determine. A lot of studies on this topic are based on observational evidence rather than controlled research and their findings are often contradictory. Most studies limit their analysis to live-births, which could underestimate the severity of teratogenic effects leading to abortions or terminations of pregnancy. The study presented in this journal club addresses these shortcomings by analyzing data on live and deceased births.
The conclusion: While some studies have shown a positive association between ADHD medications and the risk of certain birth defects, others have found no connection, and Most effective adhd medication for adults uk (
www.metooo.co.uk) studies demonstrate a neutral or slight negative effect. Therefore, a careful risk/benefit analysis must be done in each instance.
For many women with ADHD, the decision to discontinue medication can be difficult, if not impossible. In fact, in an article published in Archives of Women's Mental Health, psychologist Jennifer Russell notes that stopping
inattentive adhd medication medication during pregnancy can lead to increased depression, feelings of isolation and family conflict for these patients. A loss of medication may also impact the ability to drive safely and perform work-related tasks, which are crucial aspects of everyday life for those suffering from ADHD.
She suggests that women who aren't sure whether to take the medication or stop it due to their pregnancy educate family members, colleagues, and acquaintances about the condition, the impact on daily functioning and the benefits of continuing the current treatment plan. It can also help a woman feel confident about her decision. It is important to remember that certain medications are able to be absorbed through the placenta so if a woman decides to stop taking her ADHD medication during pregnancy and breastfeeding, she should be aware that the effects of the medication could be transferred to the child.
Birth Defects and Risk of
As the use and use of ADHD medications to treat the symptoms of attention deficit disorder hyperactivity disorder (ADHD), increases the concern over the potential adverse effects of the drugs on the fetuses. A recent study published in the journal Molecular Psychiatry adds to the body of knowledge about this subject. Researchers used two huge data sets to study over 4.3 million pregnant women and determine if stimulant medication use caused birth defects. Researchers discovered that although the risk overall is low, first-trimester
ADHD medication exposure was associated with slightly higher rates of specific heart defects like ventriculoseptal defects.
The researchers of the study found no association between early medication use and other congenital anomalies, like facial clefting, or club foot. The results are in the same vein as previous studies which showed the existence of a slight, but significant increase in the number of cardiac malformations among women who started taking ADHD medication prior to the time of pregnancy. This risk increased during the latter half of pregnancy when a large number of women stopped taking their medication.
Women who were taking ADHD medication in the first trimester were more likely to need a caesarean, have a low Apgar after delivery, and have a baby who needed help breathing at birth. The authors of the study could not remove bias in selection since they limited the study to women who did not have any other medical conditions that could have contributed to the findings.
Researchers hope that their study will provide doctors with information when they meet pregnant women. The researchers suggest that while discussing benefits and risks are important, the decision regarding whether or not to stop medication should be made in light of the severity of each woman's ADHD symptoms and her requirements.
The authors caution that, while stopping the medication is a possibility to look into, it is not recommended due to the high prevalence of depression and other mental problems among women who are pregnant or have recently given birth. Further, research shows that women who stop taking their medication will have a harder transitioning to life without them after the baby is born.
Nursing
The responsibilities that come with being a new mother can be overwhelming. Women with ADHD may face a lot of challenges when they must deal with their symptoms, go to doctor appointments, prepare for the birth of a baby and adjust to a new routine. Many women opt to continue taking their ADHD medication during pregnancy.
The risk for nursing infant is low because the majority of stimulant medications is absorbed through breast milk at a low level. The rate of exposure to medication will vary based on the dosage and frequency of administration as well as the time of the day. Additionally, different medications are introduced into the baby's system via the gastrointestinal tract or breast milk. The impact on a newborn's health is not fully known.
Some doctors may stop taking stimulant medications during a woman's pregnancy due to the lack of research. This is a difficult choice for the patient, who must weigh the benefit of continuing her medication against the potential dangers to the embryo. In the meantime, until more information is available, doctors should inquire with all pregnant patients about their experience with ADHD and if they are taking or planning to take medication during the perinatal period.
Numerous studies have proven that women can continue to take their ADHD medication in a safe manner during pregnancy and breast-feeding. In response, a rising number of patients are opting to do so. They have discovered through consultation with their doctors, that the benefits of keeping their current medication far outweigh any risk.
Women with ADHD who plan to breastfeed should seek the advice of an expert psychiatrist prior to becoming pregnant. They should discuss their medication with their doctor and discuss the pros and cons for continuing treatment. This includes non-pharmacological strategies. Psychoeducation is also necessary to help pregnant women suffering from ADHD recognize the signs and underlying disorder. They should also be informed about treatment options and build strategies for coping. This should be a multidisciplinary effort with the GPs, obstetricians, and psychiatry. Pregnancy counseling should include a discussion of a treatment plan for the mother and child, and monitoring for signs of deterioration and, if needed adjustments to the medication regimen.